The addition of ondansetron to a oral rehydration protocol for children with acute gastroenteritis.
نویسندگان
چکیده
This study describes the introduction of Ondansetron to an established waiting room Oral Rehydration Therapy (ORT) for Emergency Department (ED) children with acute gastroenteritis, and evaluates its impact on intravenous fluid administration and admissions. Children who failed initial ORT while waiting further medical assessment received Ondansetron and ORT reattempted. Data collected over a six week period in 2009 was compared to a similar period in 2008 when children received ORT without an anti-emetic. Outcome measures included intravenous fluid administration, admission. Rates of IVF administration reduced by 19% [88/215 (40.9%) in 2008, 51/234 (21.7%) in 2009, p < 0.0001] with a 1.6% reduction in admission rates [31/215 (14.41%) vs 30/234(12.82%) p=0.62]. Thirty four patients received Ondansetron, 79% were successfully rehydrated orally. The addition of Ondansetron to our established ORT programme has successfully reduced rates of IVF administration and admissions in children with gastroenteritis.
منابع مشابه
Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial
The use of antiemetics for vomiting in acute gastroenteritis in children is still a matter of debate. We conducted a double-blind randomized trial to evaluate whether a single oral dose of ondansetron vs domperidone or placebo improves outcomes in children with gastroenteritis. After failure of initial oral rehydration administration, children aged 1-6 years admitted for gastroenteritis to the ...
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OBJECTIVE The aim of this study was to determine the effect of oral ondansetron in decreasing the vomiting due to acute gastroenteritis in children. METHODS In a single center, randomized, double blind, controlled trial, the effect of oral ondansetron was compared with placebo on 176 patients between 1 and 10 years old with acute gastroenteritis. 30 minutes after drug administration, oral reh...
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BACKGROUND Vomiting limits the success of oral rehydration in children with gastroenteritis. We conducted a double-blind trial to determine whether a single oral dose of ondansetron, an antiemetic, would improve outcomes in children with gastroenteritis. METHODS We enrolled 215 children 6 months through 10 years of age who were treated in a pediatric emergency department for gastroenteritis a...
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Acute gastroenteritis is one of the most common infectious diseases of childhood. Its symptoms are vomiting, diarrhea, and dehydration. In the emergency ward, intravenous rather than oral rehydration is usually preferred because of the high likelihood of emesis. Treatments to reduce emesis are of value in improving the rehydration procedure. Our study is a double-blind randomized trial and prop...
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ورودعنوان ژورنال:
- Irish medical journal
دوره 106 9 شماره
صفحات -
تاریخ انتشار 2013